• EDUCATIONAL PROFILE

    • Ph.D (2022); Chemistry CSIR-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Thiruvananthapuram, Kerala, India.
    • Thesis: Transition Metal-Free Transformations of α,β-Unsaturated Ketones to Heterocycles of Medicinal Relevance.
    • M.Sc. (2014) Chemistry St. Joseph’s College, Devagiri, University of Calicut, Kerala.
    • B.Sc. (2012); Chemistry St. Joseph’s College, Devagiri, University of Calicut, Kerala

    CAREER DETAILS

    • April 2025 – Till Date: Scientist B, CWRDM, Kozhikode, Kerala, India.
    • September 2023 - 2024: Assistant Professor on contract basis, Department of Chemistry, University of Kerala, Thiruvananthapuram, Kerala, India.

    AWARDS

    • Best poster award at the CSIR- Inter-Institutional Students Conference (SU-CHEM Yuva,) held at CSIR-IICT, Hyderabad, India, 24-26 July 2019.
    • Senior Research Fellowship (SRF) University Grants Commission, India, 2016 August.
    • Junior Research Fellowship (JRF) and National Eligibility Test (NET) for College Lecturer with All India Rank 64, University Grants Commission, India, 2014 December

Integrated Management and Restoration Plan for Mampuzha Basin – Phase 1
Principal Investigator:
Devanand M R, Dr. Ashitha K T, Faisal Rahman P
Funding Agency:
Kunnamangalam Block Panchayath
Project Type:
Externally Funded
Duration:
3 Months
Budget:
Rs. 2.36 Lakhs
Synthesis and biological evaluation of small-molecule-based anti-biofilm agents to manage biofilm formation in potable water (SEED grant project)
Principal Investigator:
Dr. Ashitha K T
Funding Agency:
SEED GRANT, KSCSTE
Duration:
1 Year
Budget:
Rs. 5 Lakhs
Details

Ashitha, K. T.; Lakshmi, S.; Anjali, S.; Ajay Krishna; Ved Prakash; Anbumani, S.; Priya, S.; Sasidhar, B. S. Design and discovery of carboxamide-based pyrazole conjugates with multifaceted potential against Triple-Negative Breast cancer MDA-MB-231 cells. Bioorg. Med. Chem. Lette., 2024, 113 129960, https://doi.org/10.1016/j.bmcl.2024.129960.

Ashitha, K. T.; Krishna, A.; Basavaraja, D.; Sasidhar, B. S. Recent advances in the transition metal-free synthesis of heterocycles from α, β-unsaturated ketones. Org. Chem. Front., 2022, 9, 5306-5357. https://doi.org/10.1039/D2QO00278G.

Ashitha, K. T.; Vinaya, P. P.; Krishna, A.; Vincent, D. C.; Jalaja, R.; Varughese, S.; Somappa, S. B. I2/TBHP mediated diastereoselective synthesis of spiroaziridines. Org. Biomol. Chem. 2020, 18, 1588–1593. https://doi.org/10.1039/C9OB02711D.

Ashitha, K. T.; Praveen Kumar, V.; Fathimath Salfeena, C. T.; Sasidhar, B. S. BF3·OEt2 mediated tandem annulation: A strategy to construct functionalized chromeno- and pyrano-fused pyridines. J. Org. Chem. 2018, 83, 113–124. https://doi.org/10.1021/acs.joc.7b02463.
As Co-author
Details

Ajay Krishna M. S.; Ashitha, K. T.; Prabhakara Bhat. M.; Rudrappa, M.; Sandhya, K. S.; Lima, N. C.; Basavaraja, D.; Varughese, S.; Nayaka, S.; Somappa, S. B. Dual-acting β-Aminothiochoromones; Design, synthesis, and evaluation as antimicrobial and anti-angiogenic agents. Bioorg. Med. Chem. Lett. 2025, 130140. https://doi.org/10.1016/j.bmcl.2025.130140

Basavaraja, D.; Athira, C. S.; Siddalingeshwar V. D.; Ashitha, K. T. Multicomponent synthesis of spiro-dihydropyridine oxindoles via cascade spirocyclization of Knoevenagel/aza-Michael adducts. J. Org. Chem. 2022, 87, 13556–13563. https://doi.org/10.1021/acs.joc.2c01063.

Ajay Krishna, M. S.; Mohan, S.; Ashitha, K. T.; Chandramouli, M.; Kumaran, A.; Ningaiah, S.; Babu, S.; Sasidhar, B. S. Marine based natural products: Exploring the recent developments in the identification of antimicrobial agents. Chem. Biodiversity 2022, 19, e202200513. https://doi.org/10.1002/cbdv.202200513.

Fathimath Salfeena, C. T.; Basavaraja; Ashitha, K. T.; Kumar, V. P.; Varughese, S.; Suresh, C. H.; Sasidhar, B. S. Synthesis of symmetrical and unsymmetrical triarylpyrylium ions: via an inverse electron demand Diels-Alder reaction. Chem. Commun. 2018, 54, 12463–12466. https://doi.org/10.1039/C8CC06444J.

Mohan, B.; Salfeena, C. T. F.; Ashitha, K. T.; Krishnan, G. V.; Jesmina, A. R. S.; Varghese, A. M.; Patil, S. A.; Kumar, B. N. S. D.; Sasidhar, B. S. Functionalized pyrimidines from alkynes and nitriles: Application towards the synthesis of marine natural product meridianin analogs. ChemistrySelect 2018, 3, 6394–6398. https://doi.org/10.1002/slct.201801126.

Jalaja, R.; Leela, S. G.; Valmiki, P. K.; Salfeena, C. T. F.; Ashitha, K. T.; Krishna Rao, V. R. D.; Nair, M. S.; Gopalan, R. K.; Somappa, S. B. Discovery of natural product derived labdane appended triazoles as potent pancreatic lipase inhibitors. ACS Med. Chem. Lett. 2018, 9, 662–666. https://doi.org/10.1021/acsmedchemlett.8b00109.

Fathimath Salfeena, C. T.; Ashitha, K. T.; Sasidhar, B. S. BF3·Et2O Mediated one-step synthesis N-substituted-1,2-dihydropyridines, indenopyridines and 5,6-dihydroisoquinolines. Org. Biomol. Chem. 2016, 14, 10165–10169. https://doi.org/10.1039/C6OB02133F.
BF3·OEt2-Mediated tandem annulation: A strategy to construct functionalized chromeno and pyrano fused pyridines. Poster presentation at XIV J-NOST Conference for Research Scholars held at CSIR-IICT, Hyderabad, India, 28 November – 1 December 2018.

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